Prostate Cancer
*** A list of abbreviations is provided at the end of this note. Background: Most commonly diagnosed non-cutaneous malignancy in men Second leading cause of cancer death among men in the US Key risk factors: Age: mostly in men >50 (median age at diagnosis ~66) Family history: first-degree relative increases the risk 2-3 times Race: significantly higher incidence in African American, earlier onset and 2× mortality No biological differences in tumor genomics Germline mutations: