B-Cell Non-Hodgkin Lymphoma (NHL)
Introduction: NHL is categorized into two groups of B-cell lymphomas and T/NK-Cell lymphomas: B-cell lymphomas (85–90%): Aggressive: Diffuse large B-cell lymphoma (DLBCL) High-grade B-cell lymphoma (HGBL) Includes selected lymphomas with MYC and BCL2 rearrangements Historically referred to as “double-hit” lymphoma when MYC and BCL2 rearrangements are present Burkitt lymphoma (BL): Highly aggressive Derived from germinal center B cells Mantle cell lymphoma (MCL): Generally cli